- Biochemistry. any substance that interferes with growth of an organism by competing with or substituting for an essential nutrient in an enzymatic process.
- Pharmacology. of or relating to certain substances used to prevent or reduce the proliferation of cells, especially cancer cells, by interfering with normal metabolic activity.
- any drug that acts by disrupting the normal growth of a cell. Sulfonamide drugs are antimetabolites and some antimetabolites are used in cancer treatment
- A substance that closely resembles an essential metabolite and competes with, interferes with, or replaces the metabolite in physiological reactions.