chancre

noun Pathology.

1. the initial lesion of syphilis and certain other infectious diseases, commonly a more or less distinct ulcer or sore with a hard base.

noun

1. pathol a small hard nodular growth, which is the first diagnostic sign of acquired syphilis

n.

1. The primary lesion of syphilis; a hard, nonsensitive, dull red papule or area of infiltration that begins at the site of infection after an interval of 10 to 30 days.hard chancre hard ulcer