- Gulf of, an arm of the Caribbean between NE Panama and NW Colombia.
- Isthmus of, former name of the Isthmus of Panama.
- a town in SW Connecticut.
- a city in NE Illinois.
- the E part of the Isthmus of Panama, between the Gulf of Darien on the Caribbean coast and the Gulf of San Miguel on the Pacific coast; chiefly within the republic of Panama but extending also into Colombia: site of a disastrous attempt to establish a Scottish colony in 1698
- Isthmus of Darien the former name of the Isthmus of Panama