verb (used with object), de·na·tured, de·na·tur·ing.
- to deprive (something) of its natural character, properties, etc.
- to render (any of various alcohols) unfit for drinking by adding an unwholesome substance that does not alter usefulness for other purposes.
- Biochemistry. to treat (a protein or the like) by chemical or physical means so as to alter its original state.
- to make (fissionable material) unsuitable for use in an atomic weapon by mixing it with unfissionable material.
- to change the nature of
- to change (a protein) by chemical or physical means, such as the action of acid or heat, to cause loss of solubility, biological activity, etc
- to render (something, such as ethanol) unfit for consumption by adding nauseous substances
- to render (fissile material) unfit for use in nuclear weapons by addition of an isotope
1878, in modern sense, from French dénaturer (Old French desnaturer “change the nature of; make unnatural”); see de- + nature. Earlier “to make unnatural” (1680s). Related: Denatured.
- To change the nature or natural qualities of.
- To render unfit to eat or drink without destroying usefulness in other applications, especially adding methyl alcohol to ethyl alcohol.
- To alter the chemical structure of a protein, as with heat, alkali, or acid, so that some of its original properties, especially its biological activity, are diminished or eliminated.
- To cause the tertiary structure of a protein to unfold, as with heat, alkali, or acid, so that some of its original properties, especially its biological activity, are diminished or eliminated.
- To cause the paired strands of DNA to separate into individual strands.