noun Cell Biology.

  1. the last stage in prophase, in which the nucleolus and nuclear envelope disappear, spindle fibers form, and the chromosomes shorten in preparation for anaphase.


  1. the final stage of the prophase of meiosis, during which homologous chromosomes start to separate after crossing over


  1. The final stage of the prophase in meiosis, characterized by shortening and thickening of the paired chromosomes, formation of the spindle fibers, disappearance of the nucleolus, and degeneration of the nuclear membrane.

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