- a combining form with the meanings “large, great, grand,” “abnormally large,” used in the formation of compound words: megalopolis; megalocardia.
- indicating greatness, or abnormal sizemegalopolis; megaloblast
word-forming element meaning “large, great, exaggerated,” from comb. form of Greek megas “large, great” (stem megal-); see mickle. pref.
- Large; of exaggerated size or greatness:megalocephaly.