![metachromatic leukodystrophy metachromatic leukodystrophy](https://www.tekportal.net/wp-content/uploads/2018/12/metachromatic-leukodystrophy.png)
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- An inherited metabolic disorder characterized by myelin loss, accumulation of metachromatic lipids in the white matter of the central and peripheral nervous systems, a marked excess of sulfatidates in white matter and in urine, progressive paralysis, and dementia.