niemann-pick disease

noun Pathology.

1. a rare, hereditary lipid-storage disease, occurring primarily among Ashkenazic Jews, in which abnormal lipid metabolism results in enlargement of the liver, spleen, and lymph nodes, and in progressive mental and physical deterioration.

n.

1. An inherited disorder of lipid metabolism characterized by gastrointestinal disturbances and enlargement and abnormalities of blood-forming organs; it occurs primarily in infants of eastern European Jewish descent and it leads to early death.Pick’s disease2 sphingomyelin lipidosis