osteogenesis imperfecta

noun Pathology.

1. a rare hereditary disease in which abnormal connective tissue development leads to fragile bones subject to fracture.

noun

1. a hereditary disease caused by a collagen abnormality, causing fragility of the skeleton which results in fractures and deformitiesAlso called: brittle bone syndrome

n.

1. A hereditary disease marked by abnormal fragility and plasticity of bone, with deformity of long bones, a bluish discoloration of the sclerae, recurring fractures resulting from minimal trauma, and often otosclerosis.brittle bones

1. A hereditary disease characterized by abnormally brittle, easily fractured bones.