scleroderma

noun Pathology.

1. a disease in which connective tissue anywhere in the body becomes hardened and rigid.

noun

1. a chronic progressive disease most common among women, characterized by a local or diffuse thickening and hardening of the skin

n.1866, from Modern Latin, from Greek skleros “hard” (see sclerosis) + derma “skin” (see derma). Related: Sclerodermatous; sclerodermatic. n.

1. A collagen disease characterized by the deposition of fibrous tissue into the skin and often other organs, causing tissue hardening and thickening.dermatosclerosis
2. progressive systemic sclerosis

1. A connective tissue disease characterized by the deposition of fibrous tissue into the skin and often other organs, causing tissue hardening and thickening.