urokinase [yoo r-uh-kahy-neys, -neyz] Word Origin noun Biochemistry, Pharmacology.
- an enzyme, present in the blood and urine of mammals, that activates plasminogen and is used medicinally to dissolve blood clots.
Origin of urokinase First recorded in 1955–60; uro-1 + kinase urokinase in Medicine urokinase [yur′ō-kī′nās, -nāz] n.
- An enzyme that catalyzes the conversion of plasminogen to plasmin and is produced in the kidney, excreted in the urine, and used to dissolve blood clots.plasminogen activator