- a fatal degenerative disease of the central nervous system characterized by progressive lack of coordination and dementia, known only among certain Melanesian peoples, especially the Fore of New Guinea, and caused by a slow virus: now virtually extinct.
- a degenerative disease of the nervous system, restricted to certain tribes in New Guinea, marked by loss of muscular control and thought to be caused by a slow virus
- A progressive, fatal spongiform encephalopathy, probably caused by a slow-acting virus, that is endemic to certain peoples of New Guinea and may be transmitted through cannibalism.
- A rare, progressive, degenerative neurological disease found in certain peoples of New Guinea and associated with cannibalism. It is thought to be caused by a prion and results in a fatal encephalopathy. See Note at prion.